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Life Sciences Division
1997-98
Progress Report

Contents

Foreword

Division

  • Overview
  • Mission
  • Structure

Systems Biology

Technology Applications

Infrastructure

Partnerships

Initiatives

Appendices

LSD Home Page

Open Literature Publications, CY 1997-1998

Adams, V., M. Bennett, L. Bishop, K. Deacon, T. Mims, R. Sheely, C. Johnson, K. L. Yuracko, P. Selby, G. Kerr, M. Gresalfi, and C. Goddard, "U.S. Department of Energy National Center of Excellence for Metals Recycle," in Proceedings of Spectrum '98, International Conference on Decommissioning and Decontamination and on Nuclear and Hazardous Waste Management, Denver, Colorado, American Nuclear Society, Inc., La Grange Park, IL, pp. 39-46 (1998).

Alberto, R., R. Schibli, U. Abram, A. Egli, F. F. Knapp, Jr., and P. A. Schubiger, "Potential of the Organometallic "[M(CO)3]+" (M = Re, Tc) Fragment for the Labeling of Proteins and Small Molecules," Radiochimica Acta 79(2), 145-49 (1997).

Allison, D. P., M. J. Doktycz, P. R. Hoyt, T. Thundat, and R. J. Warmack, "The Analysis of Genomes by Atomic Force Microscopy," Scanning 19, 136-37 (1997).

Allison, D. P., P. S. Kerper, M. J. Doktycz, T. Thundat, P. Modrich, F. W. Larimer, D. K. Johnson, P. R. Hoyt, M. L. Mucenski, and R. J. Warmack, "Mapping Individual Cosmid DNAs by Direct AFM Imaging," Genomics 41(3), 379-84 (1997).

Allison, D. P., T. Thundat, and R. J. Warmack, "Scanning Probe Microsopy in Genomic Research," in Automated Technologies for Genome Characterization, ed. T. J. Beugelsdijk. Wiley Publishers, New York, pp. 167-88 (1997).

Arakawa, E. T., P. S. Tuminello, B. N. Khare, and M. E. Milham, "Optical Properties of Horseradish Peroxidase from 0.13 to 2.5 Microns," Biospectroscopy 3(1), 73-80 (1997).

Arlinghaus, H. F., M. N. Kwoka, and K. B. Jacobson, "Analysis of Biosensor Chips for Identification of Nucleic Acids," Anal. Chem. 69, 3747-53 (1997).

Arlinghaus, H. F., M. N. Kwoka, X.-Q. Guo, and K. B. Jacobson, "Multiplexed DNA Sequencing and Diagnostics by Hybridization with Enriched Stable Isotope Labels," Anal. Chem. 69, 1510-17 (1997).

Basavarju, S. R. and T. D. Jones, "Atherosclerotic Risks from Chemicals: Part I. A Review of Toxicological Observations," Arch. Environ. Contam. Tox. 35, 152-64 (1998).

Beattie, K. L., "Analytical Microsystems: Emerging Technologies for Environmental Biomonitoring," in Biotechnology in the Sustainable Environment, ed. G. S. Sayler. Plenum Publishing Corp., New York, pp. 249-60 (1997).

Bein, K., M. Husain, J. A. Ware, L. Mucenski, R. D. Rosenberg, and M. Simons, "c-Myb Function in Fibroblasts," J. Cell Physiol. 173, 319-26 (1997).

Bergstron, K. A., C. Halldin, J. Hiltunen, C.-G. Swahn, H. Ito, N. Ginovart, H. Hall, D.W. McPherson, F. F. Knapp, Jr., S. Larsson, P.-O. Schnell, and L. Farde, "125I and 123I Labelled (e)-(-,-)-IQNP: Potential Radioligands for Visualization of M1 Muscarinic Acetylcholine Receptor in Brain. Determination of Metabolites Using HPLC," Nucl. Med. Biol. 25, 209-14 (1998).

Bililign, S., L. Liu, C. S. Feigerle, and J. C. Miller, "Metal-Ion Chemistry in Clusters Initiated by Ionization/Dissociation of Organometallic Precursors," J. Phys. Chem. 101A, 4569-79 (1997).

Bililign, S., C. S. Feigerle, and J. C. Miller, "Nonstatistical Bond Breaking in the Multiphoton Ionization/Dissociation of [Fe(CO)5]mArn Clusters," Appl. Surf. Sci. 108(15), 6312-19 (1998).

Bililign, S., C. S. Feigerle, and J. C. Miller, "Inverse Laser Ablation: Formation and Chemistry of Nanoparticles from Gaseous Precursors," Appl. Surf. Sci. 129, 344-49 (1998).

Bishop, J. B., R. W. Morris, J. C. Seely, L. A. Hughes, K. T. Cain, and W. M. Generoso, "Alterations in the Reproductive Patterns of Female Mice Exposed to Xenobiotics," Fundam. Appl. Toxicol. 40, 191-204 (1997).

Blower, P. J., A. S. Lam, M. J. O'Doherty, A. G. Kettle, A. J. Coakley, and F. F. Knapp, Jr., "Pentavalent Rhenium-188-Dimercaptosuccinic Acid for Targeted Radiotherapy: Synthesis and Preliminary Animal and Human Studies," Eur. J. Nucl. Med., 25, 613-21 (1998).

Bogard, J. S., K. L. Yuracko, M. E. Murray, R. A. Lowden, and N. L. Vaughn, "Application of Life Cycle Analysis: The Case of Green Bullets," in Spectrum '98, Proceedings of the International Conference on Decommissioning and Decontamination andon Nuclear and Hazardous Waste Management, Vol. 1, American Nuclear Society, La Grange Park, Illinois, September 13-18, 1998, pp. 382-89 (1998).

Bohn, A. A., C. S. Forsyth, N. I. Kerkvliet, and A. A. Frank, "Immunologic Effects of Cocaine in Prenatally Exposed Rats and Mice," Toxic. Lett. 91, 47-55 (1997).

Bolch, W. E., J. E. Turner, H. Yoshida, K. B. Jacobson, R. N. Hamm, and O. H. Crawford, "Product Yields from Irradiated Glycylglycine in Oxygen-Free Solutions: Monte Carlo Simulations and Comparison with Experiments," Rad. Env. Biophysics 37(3), 157-66 (1998).

Boll, R. A., S. Mirzadeh, and S. J. Kennel, "Optimization of Radiolabeling of Immunoproteins with 213Bi," Radiochim. Acta 79(2), 145-49 (1997).

Brandes, H. K., F. W. Larimer, T.-Y. S. Lu, J. Dey, and F. C. Hartman, "Roles and Microenvironments of Tryptophanyl Residues of Spinach Phosphoribulokinase," Arch. Biochem. Biophys., 352, 130-36 (1998).

Bunick, G. J., J. M. Harp, D. Timm, and B. L. Hanson, "Macromolecular Crystal Annealing: Techniques and Case Studies," The Rigaku J., 15(2), 6-13 (1998).

Campiglia, A. D., D. M. Hueber, F. Moreau, and T. Vo-Dinh, "Phosphorescence Imaging System Using an Acousto-Optic Tunable Filter and a Charge Coupled Device," Anal. Chim. Acta 346, 361-72 (1997).

Campiglia, A. D., F. Moreau, D. M. Heuber, and T. Vo-Dinh, "Phosphorescence Imaging System Using an Acousto-Optic Filter-Based Charge Coupled Device," Anal. Chim. Acta 351, 229-39 (1997).

Campiglia, A. D. and T. Vo-Dinh, "Rapid Screening Method for Cocaine and Benzoylecgonine in Saliva Samples," Anal. Chem. 372(3), 349-55 (1998).

Capitan-Vallvey, L. F., F. Ojeda, M. del Olmo, R. Avidad, A. Navalon, and T. Vo-Dinh, "Use of Transmitted Room Temperature Phosphoroscence to Improve Nalidixic Acid Determination," Appl. Spectrosc. 52(1), 101-05 (1998).

Carver, E. A. and L. Stubbs, "Zooming in on the Human-Mouse Comparative Map: Genome Conservation Re-Examined on a High-Resolution Scale," Gen. Res. 7(12), 1123-37 (1997).

Carver, E. A., L. Issel-Tarver, J. Rine, A. S. Olsen, and L. Stubbs, "Location of Mouse and Human Genes Corresponding to Conserved Canine Olfactory Receptor Gene Subfamilies," Mammal. Genome 9(5), 349-54 (1998).

Casey, D., "What Can Genetic Tests Tell Us?" The Judges Journal 36, 3-6 (1997).

Caveliers, V., P. R. Franken, F. T. Mokler, Q. Lin, H. Luo, and F. F. Knapp, Jr., "Intra-Individual Comparison of 3(R)-BMIPP and 3(S)-BMIPP Isomers in Humans," J. Nucl. Med., 39(10), 1672-75 (1998).

Chen, C. H., V. V. Golovlev, W. R. Garrett, R. V. Goedert, T. A. Wittaker, and D. W. Templeton, "Optical Power Limiting for Eye Protection from Tunable Lasers," SPIE 3146, 170-75 (1997).

Chen, C. H., N. I. Taranenko, Y. F. Zhu, C. N. Chung, and S. L. Allman, "Laser Mass Spectrometry for DNA Sequencing, Disease Diagnosis, and Fingerprinting," in Proeedings of Ultrasensitive Biochemical Diagnostics II, SPIE 2895, 70-81 (1997).

Chen, C. H., N. I. Taranenko, Y. F. Zhu, C. N. Chung, S. L. Allman, N. R. Isola, and K. J. Matteson, "Various Approaches for Sequencing Single-Stranded and Double-Stranded DNA by MALDI," in Proceedings of the 45th ASMS Conference, Palm Springs, California, p. 761 (1997).

Chen, G., K. E. Goodson, C. Griboropoulos, M. C. Hipwell, D. Liepmann, A. Majumdar, S. Maruyama, T. Thundat, C. L. Tien, and N. C. Tien, "Report of Workshop: Thermophysical Phenomena in Microscale Sensors, Devices, and Structures," Microscale Thermophysical Eng. 1(4), 267-74 (1997).

Chen, K. M., D. E. Jesson, S. J. Pennycook, T. Thundat, and R. J. Warmack, "Critical Nuclei Shapes in the Stress-Driven 2D-to-3D Transition," Phys. Rev. B 56, R1700-3 (1997).

Chen, Y.-R., F. C. Hartman, T.-Y. S. Lu, and F. W. Larimer, "D-Ribulose-5-Phosphate 3-Epimerase: Cloning and Heterologous Expression of the Spinach Gene and Purification and Characterization of the Recombinant Enzyme," Plant Physiol. 118, 199-207 (1998).

Chiang, P.-W., R. B. Zhang, L. Stubbs, L. Zhang, L. Zhu, and D. M. Kurnit, "Comparison of Murine Supt4h and a Nearly Identical Expressed, Processed Gene: Evidence of Sequence Conservation Through Gene Conversion Extending into the Untranslated Regions," Nucl. Acids Res. 26, 4960-64 (1998).

Chiang, P.-W., L. Stubbs, L. Zhang, and D. M. Kurnit, "Isolation of Murine SPT5 Homologue: Completion of the Isolation and Characterization of Human and Murine Homologues of Yeast Chromatin Structural Protein Complex SPT4, SPT5 and SPT6," Genomics 47(3), 426-28 (1998).

Cleland, W. E., T. J. Andrews, S. Gutteridge, F. C. Hartman, and G. H. Lorimer, "Mechanism of Rubisco: The Carbamate as General Base," Chem. Rev. 98(2), 549-61 (1998).

Compton, R. N., A. A. Tuinman, C. E. Klots, M. R. Pederson, and D. C. Patton, "Electron Attachment to a Negative Ion: e+C-84-C-84-2," Phys. Rev. Lett. 78, 4367-70 (1997).

Coumans, E.F.I., F. C. Visser, A. van Lingen, J. J. Bax, G. J. van der Vusse, F. F. Knapp, Jr., and G. W. Sloof, "Exponential Relationship Between DMIPP Uptake and Blood Flow in Normal and Ischemic Canine Myocardium," Nuklearmedizin 37, S54-S59 (1998).

Critser, J. K., D. Gao, and P. Mazur, "Fundamental Cryobiology of Mammalian Spermatozoa," in Tissue Banking in Reproductive Bioloby, eds., A. M. Karow, Jr., and J.K. Critser. Academic Press, New York, pp. 263-328 (1997).

Culiat, C. T., E. A. Carver, M. Walkowicz, E. M. Rinchik, N.L.A. Cacheiro, L. B. Russell, W. M. Generoso, and L. Stubbs, "Induced Mouse Chromosomal Rearrangements as Tools for Identifying Critical Developmental Genes and Pathways," Reprod. Toxicol. 11, 345-51 (1997).

Dadachova, E. and S. Mirzadeh, "The Role of Tin in the Direct Labeling of Proteins with Rhenium-188," J. Nucl. Med. Biol. 24(6), 605-08 (1997).

Dadachova, E., S. Mirzadeh, S. V. Smith, F. F. Knapp, Jr., and E. L. Hetherington, "Radiolabeling Antibodies with Holmium-166," Appl. Radiat. Isot. 48, 477-82 (1997).

Datskos, P. G., C. Tav, I. Sauers, and L. A. Pinnaduwage, "Electron Attachment to Thermally Excited Trichlorotrifluoroethane (1,1,2-C2Cl3F3)," J. Phys. D: Appl. Phys. 30, 2596-2602 (1997).

Datskos, P. G., L. A. Pinnaduwage, and J. F. Kielkopf, "Photophysical and Electron Attachment Properties of ArF-Excimer-Laser Irradiated H2," Phys. Rev. A 55, 4131-42 (1997).

Davis, A. P. and A. Kuklin, "PCR-Genotyping on DNA Extracted from a Mouse Ear-Punch Using the QIAamp Tissue Kit," Biotechnology and Biotechnological Equip. 12(1), 102-03 (1998).

Davis, A. P. and M. J. Justice, "An Oak Ridge Legacy: The Specific Locus Test and Its Role in Mouse Mutagenesis," Genetics 148, 7-12 (1998).

Davis, A. P. and M. J. Justice, "Meeting Report: 11th International Mouse Genome Conference," Mammal. Genome 9(5), 345-48 (1998).

Davis, A. P. and M. J. Justice, "Mouse Alleles: If You've Seen One, You Haven't Seen Them All," Trends in Genetics 14(11), 438-41 (1998).

Deckert, V., R. Zenobi, T. Vo-Dinh, and D. Zeisel, "Imaging of Dye-Labeled DNA with 100-nm Resolution," Anal. Chem. 70(13), 2646-50 (1998).

Deelman, P. W., L. J. Schowalter, and T. Thundat, "In Situ Measurements of Temperature-Dependent Strain Relaxation of Ge/Si(111)," J. Vac. Sci. Technol. A, 15(3), 930-34 (1997).

Deelman, P. W., L. J. Schowalter, and T. Thundat, "In Situ Measurements of Islanding and Strain Relaxation of Ge/Si(111)," Mater. Res. Soc. Symp. Proc. 441, 373-78 (1997).

Dees, C., C. C. Travis, M. Askari, J. S. Foster, and J. Wimalasena, "DDT Mimics Estradiol by Stimulating Breast Cancer Cells to Enter the Cell Cycle," Mol. Carcinog. 18, 107-14 (1997).

Deng, L., W. R. Garrett, M. G. Payne, and M. A. Moore, "Gain Suppression Involving Both Stimulated Raman and Hyper-Raman Photons in Two-Step Stimulated Emissions," Chem. Phys. Lett. 270, 299-303 (1997).

Deng, L., W. R. Garrett, and M. G. Payne, "Pressure Dependence of the AC Stark Shifts in Nitric Oxide: Resonant Multiphoton-Ionization Spectroscopy Without Space Charge," Chem. Phys. Lett. 271, 15-18 (1997).

Dhar, M. S. and D. K. Johnson, "A Microsatellite Map of the Pink-eyed dilution (p) Deletion Complex in Mouse Chromosome 7," Mammal. Genome 8, 143-45 (1997).

Dichtl, B., A. Stevens, and D. Tollervey, "Lithium Toxicity in Yeast is Due to the Inhibition of RNA Processing Enzymes," Embo. J. 16, 7184-95 (1997).

DiLeone, R. J., L. B. Russell, and D. M. Kingsley, "An Extensive 3' Regulatory Region Controls Expression of Bmp5 in Specific Anatomical Structures of the Mouse Embryo," Genetics 148, 401-08 (1998).

Ding, W., D. McCorkle, and L. A. Pinnaduwage, "Enhanced Formation of Negative Ions by Electron Attachment to High-Excited Molecules in a Flowing Afterflow Plasma," J. Appl. Phys. 84(6), 3051-58 (1998).

Doktycz, M. J. and K. L. Beattie, "Genosensors and Model Hybridization Studies," in Automated Technologies for Genome Characterization, ed. T. J. Beugeldsdijk. John Wiley & Sons, Inc., New York, pp. 205-25 (1997).

Doktycz, M. J., F. W. Larimer, M. Pastrnak, and A. Stevens, "Comparative Analyses of the Secondary Structures of Synthetic and Intracellular Yeast MFA2 mRNAs," Proc. Natl. Acad. Sci. USA 95, 14014-22 (1998).

Doyle, J., X. J. Ren, G. Lennon, and L. Stubbs, "Mutations in the Cacnl1a4 Calcium Channel Gene are Associated with Seizures, Cerebellar Degeneration, and Ataxia in Tottering and Leaner Mutant Mice," Mammal. Genome 8(2), 113-20 (1997).

Doyle, J. L. and L. Stubbs, "Ataxia, Arrhythia, and Ion Channel Gene Defects," Trends Genet. 14, 92-98 (1998).

Easterly, C. E., G. O. Allgood, K. Eckerman, H. Knee, M. Maston, G. McNeilly, J. Munro, N. Munro, R. Toedte, B. Van Hoy, and R. Ward, "Virtual Human: A Diagnostic Tool for Human Studies and Health Effects in the 21st Century," in Biomedical Sensing and Imaging Technologies, eds., R. A. Leiberman and T. Vo-Dinh. Proceedings of SPIE, Vol. 3253, pp. 150-54 (1998).

Egidi, P. V., "The Independent Verification Process in Decommissioning, Decontamination, and Reutilization Activities - Description, Benefits, and Lessons Learned," in Proceedings of the American Nuclear Society Meeting on Decommissioning, Decontamination and Reutilization, Knoxville, Tennessee, September 7-12, 1997, American Nuclear Society, pp. 535-39 (1997).

Eigler, N., J. Whiting, R. Makkar, H. A. Hidehiko, F. F. Knapp, Jr., and F. Litvack, "RADIANT™ Liquid Isotope Intravascular Radiation Therapy System," in Proceedings, Symposium on Advances in Cardiovascular Radiation Therapy, Washington, D.C., March 8-10, 1998, pp. 234-37 (1998).

Eres, G., Y.-C. Hui, T. Thundat, and D. C. Joy, "Direct Epitaxial Growth of Thin-Film Structures," J. Vac. Sci. Tech. B 15(6), 2934-39 (1997).

Eres, G., Y.-C. Hui, T. G. Thundat, and D. C. Joy, "Nanofabrication by Direct Epitaxial Growth," Microelectronic Eng. 42, 519-22 (1998).

Feigerle, C. S., L. Liu, M. Z. Martin, S. R. Desai, and J. C. Miller, "Multiphoton Ionization Studies of Laser-Induced Chemistry in Clusters," in Resonance Ionization Spectroscopy 1996, eds., N. Winograd and J. E. Parks. American Institute of Physics, New York, p. 387 (1997).

Fell, T. P., J. D. Harrison, and R. W. Leggett, "A Model for the Transfer of Alkaline Earth Elements to the Fetus," Radiat. Prot. Dosim. 79, 343-50 (1998).

Feng, B., A. Gorin, B. E. Hingerty, N. E. Geacintov, S. Broyde, and D. A. Patel, "Structural Alignment of the (+)-trans-anti-Benzo[a]pyrene-dG Adduct Positioned Opposite dC at a DNA Template-Primer Junction," Biochemistry 36, 13769-79 (1997).

Feng, B., A. Gorin, A. Kolbanovskiy, B. E. Hingerty, N. E. Geacintov, S. Broyde, and D.J. Patel, "Solution Conformation of the (-)-trans-anti-[BP]dG Adduct Opposite a Delection Site in a DNA Duplex: Intercalation of the Covalently Attached Benzo[a]pyrene into the Helix with Base Displacement of," Biochemistry 36, 13780-90 (1997).

Ferrell, T. L., P. B. Crilly, S. F. Smith, A.L. Wintenberg, C. L. Britton, G. W. Morrison, M. N. Erickson, D. Hedden, D. Bouldin, A. Passian, T. Downey, A. Wig, and F. Meriaudeau, "Medical Telesensors," SPIE 3253, 193-98 (1998).

Fields, D. E. and V. M. F. Jacomino, "A Critical Approach to the Calibration of a Watershed Model," J. Am. Water Resour. Assoc. 33, 143-54 (1997).

Fisher, W. G., E. A. Wachter, M. Armas, and C. Seaton, "The Titanium:Sapphire Laser as an Excitation Source in Two-Photon Spectroscopy," Appl. Spectrosc. 51, 218-26 (1997).

Fisher, W. G., W. P. Partridge, Jr. , C. Dees, and E. A. Wachter, "Simultaneous Two-Photon Activation of Type-I Photodynamic Therapy Agents," Photochem. Photobiol. 66, 141-55 (1997).

Fisher, W. G., K. E. Meyer, E. A. Wachter, D. R. Perl, and P. J. Kulowitch, "Laser Induced Fluorescence Imaging of Heat Damage in Polymer Matrix Composites," Mater. Eval. 55, 726-36 (1997).

Fisher, W. G., E. A. Wachter, F. E. Lytle, M. Armas, and C. Seaton, "Source-Corrected Two-Photon Excited Fluoroscence Measurements Between 700 and 880 nm," Appl. Spectros. 52(4), 536-45 (1998).

Fritschy, J. M., D. Benke, D. K. Johnson, H. Mohler, and U. Rudolph, "GABAA-Receptor Alpha-Subunit is an Essential Prerequisite for Receptor Formation in vivo," Neurosci. 81(4), 1043-53 (1997).

Fritschy, J.-M., D. K. Johnson, H. Mohler, and U. Rudolph, "Independent Assembly and Subcellular Targeting of GABAA-Receptor Subtypes Demonstrated in Mouse Hippocampal and Olfactory Neurons In Vivo," Neurosci. Lett. 249(2-3), 99-102 (1998).

Funderburgh, J. L., A. L. Perchellet, P. Swiergiel, G. W. Conrad, and M. J. Justice, "Keratocan (Kera), a Corneal Keratan Sulfate Proteoglycan, Maps to the Distal End of Mouse Chromosome 10," Genomics 52(1), 110-11 (1998).

Geacintov, N. E., M. Cosman, B. E. Hingerty, S. Amin, S. Broyde, and D. J. Patel, "NMR Solution Structures of Stereoisomeric Polycyclic Aromatic Carcinogen-DNA Adducts: Principles, Patterns, and Diversity," Chem. Res. Toxicol 10, 111-46 (1997).

Geisler, J. G., L. J. Stubbs, W. W. Wasserman, and M. L. Mucenski, "Molecular Cloning of a Novel Mouse Gene with Predominant Muscle and Neural Expression," Mammal. Genome 9(4), 274-82 (1998).

Golovlev, V., S. Allman, W. R. Garrett, N. I. Taranenko, and C. H. Chen, "Laser Induced Acoustic Desorption," Int. J. Mass Spectrom. Ion Processes 169, 69-78 (1997).

Golovlev, V. V., S. L. Allman, W. R. Garrett, and C. H. Chen, "Laser-Induced Acoustic Desorption of Electrons and Ions," Appl. Phys. Lett. 71, 852-54 (1997).

Grad, R., R. Shapire, B. E. Hingerty, S. Broyde, "A Molecular Mechanics and Dynamics Study of the Minor Adduct Between DNA and the Carcinogen 2-(Acetylamino)fluorene (dG-N-2-AAF)," Chem. Res. Toxicol. 10(1), 1123-32 (1997).

Grant, W. F. and E. T. Owens, "Chromosome Aberration Assays in Crepis for the Study of Environmental Mutagens," Mutation Res. 410, 291-307 (1998).

Guhlke, S., P. O. Zamora, J. Sartor, F. F. Knapp, Jr. , H. Bender, B. A. Rhodes, and H.-H. Biersack, "Ascorbic Acid Stabilization of Re-188- and I-131-Radiolabeled Peptides for Radiotherapy," Radiochim. Acta 79, 93-97 (1997).

Guhlke, S., A. Schaffland, P. O. Zamora, J. Sartor, D. Diekmann, H. Bender, F. F. Knapp, and H.-J. Biersack, "188Re- and 99mTc-MAG3 as Prosthetic Groups for Labeling Amines and Peptides: Approaches with Pre- and Post-Conjugate Labeling," Nucl. Med. Biol. 25, 621-31 (1998).

Hamm, R. N., J. E. Turner, and M. G. Stabin, "Monte Carlo Simulation of Diffusion and Reaction in Water Radiolysis - A Study of Reactant "Jump Through" and Jump Distances," Radiat. Environ. Biophys. 36, 229-34 (1998).

Hamm, R. N., M. G. Stabin, and J. E. Turner, "Investigation of Monte Carlo Models for Chemical Reactions," Radiat. Environ. Biophys. 37(3), 151-56 (1998).

Hansen, G. M. and M. J. Justice, "Pten, a Candidate Tumor Suppressor Gene, Maps to Mouse Chromosome 19," Mammal. Genome 9, 88-90 (1998).

Harp, J. M., D. E. Timm, and G. J. Bunick, "Macromolecular Crystal Annealing: Overcoming Increased Mosaicity Associated with Cryocrystallography," Acta Crystallogr. D 54, 622-28 (1998).

Harpel, M. R., F. W. Larimer, and F. C. Hartman, "Multiple Catalytic Roles of His287 of Rhodospirillum rubrum Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase," Protein Sci. 7, 730-38 (1998).

Hartman, F. C., "Finn Wold (1928-1997)," Protein Sci. 6, 2271-72 (1997).

Hasan, A., K.-P. Stengele, H. Giegrich, P. Cornwell, K. W. Isham, R. A. Sachleben, W. Pfleiderer, and R. S. Foote, "Photolabile Protecting Groups for Nucleosides: Synthesis and Photodeprotection Rates," Tetrahedron 53, 4247-64 (1997).

Hasan, J. S., T. D. Jones, and M. D. Morris, "MarCell™ Software for Modeling Bone Marrow Radiation Cell Kinetics," Med. Phys. 24, 1793-96 (1997).

Hirasawa, M., H. K. Brandes, F. C. Hartman, and D. B. Knaff, "Oxidation-Reduction Properties of the Regulatory Site of Spinach Phosphoribulokinase," Arch. Biochem. Biophys. 350, 127-31 (1998).

Hosono, M. N., M. Hosono, P. O. Zamora, S. Guhlke, T. Haberberger, H. Bender, F. F. Knapp, Jr., and H.-J. Biersack, "Localization of Colerectal Carcinoma by Rhenium-188-Labeled B72.3 Antibody in Xenografted Mice," Annals Nucl. Med. 12, 83-88 (1998).

Hoyt, P. R., C. Bartholomew, L. W. Gamer, C.V.E. Wright, S. S. Potter, J. N. Ihle, and M. L. Mucenski, "The Evi-1 proto-oncogene is required at midgestation for neural, heart, and paraxial mesenchyme development," Mech.Dev. 65, 55-70 (1997).

Huang, J.-D., V. Mermall, M. C. Strobel, L. B. Russell, M. S. Mooseker, N. G. Copeland, and N. A. Jenkins, "Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Tail Region Mutations," Genetics 148, 1963-72 (1998).

Huang, J.-D., M.J.T.V. Cope, V. Mermall, M. C. Strobel, J. Kendrick-Jones, L. B. Russell, M. S. Mooseker, N. G. Copeland, and N. A. Jenkins, "Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Head Region Mutations," Genetics 148, 1951-61 (1998).

Huang, L.-F., N. Fukai, P. B. Selby, B. R. Olsen, and S. Mundlos, "Mouse Clavicular Development: Analysis of Wild-Type and Cleidocranial Dysplasia Mutant Mice," Dev. Dyn. 210, 33-40 (1997).

Hurst, G. B., K. Weaver, M. J. Doktycz, M. V. Buchanan, A. M. Costello, and M. E. Lidstrom, "MALDI-TOF Analysis of Polymerase Chain Reaction Products from Methanotrophic Bacteria," Anal. Chem. 70, 2693-98 (1998).

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Isfort, R. J., D. B. Cody, W. G. Richards, B. K. Yoder, J. E. Wilkinson, and R. P. Woychik, "Characterization of Growth Factor Responsiveness and Alterations in Growth Factor Homeostasis Involved in the Tumorigenic Conversion of Mouse Oval Cells," Growth Factors 15, 81-94 (1998).

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Jones, T. D., "On 'Toxicity Equivalent Factors' and 'Relative Potency' to Account for Differential Toxicity and Carcinogenicity: Concerns about Uncommon Effects of Dose in Animal Experiments and Environmental Exposures to Humans," Environmentrics 9, 525-39 (1998).

Jones, T. D., M. D. Morris, and S. R. Basavarju, "Atherosclerotic Risks from Chemicals: Part II. A RASH Analysis of in vitro and in vivo Test Data to Evaluate 45 Potentially Hazardous Compounds," Arch. Environ. Contam. Tox. 35, 164-77 (1998).

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Lin, Q., H. Luo, F. Mokler, A. L. Beets, K. R. Ambrose, D. W. McPherson, J. Kropp, and F. F. Knapp, Jr., "Effects of Configuration on the Myocardial Uptake of Radioiodinated 3(R)-BMIPP and 3(S)-BMIPP," J. Nucl. Med. 38, 1434-40 (1997).

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Luo, H., A. L. Beets, K. R. Ambrose, D. W. McPherson, and F. F. Knapp, Jr., "Synthesis, In Vitro and In Vivo Evaluation of Fluorine-18-Labeled (R,R)- and (R,S)-Isomers of FQNPe - New Candidates for Muscarinic-Cholinergie Receptor Imaging by PET," J. Lab Radiopharm.Compds. XLI, 681-704 (1998).

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