Life Sciences Division
1997-98
Progress Report

Contents

Foreword

Division

• Overview
• Mission
• Structure

Systems Biology

• Biochemistry & Biophysics
• Computational Biosciences
• Mammalian Genetics & Development

Technology Applications

• Assessment Technology
• Environmental Technology
• Toxicology & Risk Analysis

Infrastructure

• Lab Animal Resources
• Operations & Support
• Mouse Genetics Research
• DNA Sequencing Lab
• Gene Expression Chip Lab
• Dosimetry & Biokinetic
• Life Cycle Analysis
• Environmental Assessment

Partnerships

• Biological Sciences Institute
• Genome Science & Tech
• Tenn Mouse Genome Consortium

Initiatives

• Biological Sciences
• Functional Genomics & Proteomics
• Structural Biology
• Biomedical Engineering
• Technology Applications

Appendices

• Demographics
• Budget
• Division Pubs
• Open Literature Pubs
• ORNL & Misc. Reports
• Presentations
• U.S. Patents
• Invention Disclosures
• Honors, Awards, etc.
• Advisory Committee

LSD Home Page

Life Sciences Division

Administrative Office Staff

• Reinhold C. Mann, Division Director
  • Susan A Masingo, Division Secretary
  • Brenda H. Kimmel, Secretary
  • Beverly W. Selmer, Secretary¹
  • Linda S. Wells, Secretary¹
• Barry A. Berven, Associate Division Director
  • Debbie Dickerson, Senior Secretary
• Waldean Richardson, Administrative Assistant
• Cheryl D. Parks, Finance Officer²
  • Ursula F. Harris, Accounting Assistant
  • Diane Johnson, Secretary

_________________

¹Retired or terminated employment with Life Sciences Division in 1997 or 1998
²Finance and Business Management Division

******************************************

Overview

The Life Sciences Division was created in February 1997 by merging the Biology and Health Sciences Research Divisions. It continues the ORNL tradition of excellence in biomedical research that started 50 years ago. Building on strong and often unique competencies and special facilities in Mammalian Genetics, Molecular Biology, Biochemistry and Biophysics, Structural Biology, Bioinformatics, Biomedical Technology, Biotechnology, Environmental Assessment Technologies, Risk Analysis, and Toxicology, the division pursues research and development to understand the impact of energy production and use on biological systems in general and on human health in particular. The division provides a stimulating R&D environment for a multi-disciplinary group of approximately 480 staff members, including researchers, support staff, subcontractors, guests, and students who pursue challenging research at the intersection of the Biological, Physical, Medical, Engineering, and Computational Sciences. The division operates the MGRF, an official Department of Energy User Facility. It consists of a colony of approximately 500 genetic strains of mice with a total of approximately 70,000 animals, and co-located well equipped laboratory space. This mutant collection is a resource for research in analyzing gene function and identifying mouse models of human genetic diseases. The division has modern experimental research laboratories that support research in the core biosciences and technology development in biosensing, molecular imaging, and high-throughput genotyping. State-of-the-art computing and information processing facilities are part of the division infrastructure supporting Bioinformatics and Computational Biology research programs.

Mission

The mission of the Life Sciences Division is to advance science and technology in order to understand complex biological systems and their relationship with human health and the environment.

Structure

The Life Sciences Division consists of six research sections, an operations support section, and the Laboratory Animal Resources Section, which operates the MGRF.